“If
any of your loved ones is suffering from a genetic disorder like AIDS, Sickle
cell Anemia, or Hemophilia. Doctors and scientists are positive about the cure
of such diseases through Genome Editing, but they are helpless due to the ban
on genome editing in Humans.” How would you feel?
Introduction
Due to the advancements in science and technology, we
have achieved marvels in every field. Let's take an example of genetic
mutation, in the field of Agriculture we are now able to grow unseasoned
vegetables and fruits. Have achieved good breeds in Animals. However, this
technique is banned from even treating the lifelong diseases that pass on
through generation to generation. Genome editing, particularly through
techniques like CRISPR-Cas9, modifies the DNA (Deoxy Ribo nuclic Acid )
sequences in an organism . This is done to the disease-carrying genes, and
transform it .This has completely revolutionized molecular biology. However,
alongside its potential benefits, genome editing raises ethical, safety, and
social concerns.
Genome Editing
Research in Genome Editing might do
Wonders.
Genome editing in humans can treat and cure many
genetic illnesses. Genome
editing is a tool that needs further genomic editing of nucleases. Porteus, M.
(2016). In Humans Genome editing enables researchers to edit the target section
of DNA sequence. De
Lecuona, I., Casado, M., Marfany, G., Baroni, M. L., & Escarrabill, M.
(2017).Clinical trials have already shown promising results,
indicating that gene editing can effectively treat certain diseases (Ledford,
2015).
Genome Editing might be risky.
Despite the positive outcome of genome editing in
humans. we need to address why people on a large scale are against it. One of
the main reasons is if it goes wrong then we will have to bear long-term
consequences. For instance, Elephant babies, apes like humans, and Dogman. Despite
its precision, genome editing is not without risks. Off-target effects, where
unintended parts of the genome are altered, could potentially lead to harmful
mutations (Zhang, 2019).
Genome Editing is morally unacceptable
As we know that most of the world population lives in
a poverty stricken or war-torn areas, who could not enjoy the benefits of this
advancement. They might become the guinea pigs of the scientists and wealthy
people might fester on them. So this is morally unacceptable as this would be disproportionate
and create fissures in the communities. Genome editing in humans might result in
unintended harm the
basic question is whether this should be done without compromising the self-esteem of
any individual or nation. Hynes, R.
O., Coller, B. S., & Porteus, M. (2017).
The long-term effects of genome editing are also unknown, raising concerns about unforeseen consequences for individuals and future generations.
Conclusion
 |
| genome editing is done on the targetted gene |
## References
De Lecuona, I., Casado, M.,
Marfany, G., Baroni, M. L., & Escarrabill, M. (2017). Focus: genome
editing: gene editing in humans: towards a global and inclusive debate for
responsible research. The Yale Journal of Biology and Medicine, 90(4),
673.
Hynes, R. O., Coller, B. S.,
& Porteus, M. (2017). Toward responsible human genome editing. Jama, 317(18),
1829-1830.
Ledford, H. (2015). CRISPR, the disruptor. Nature, 522(7554), 20-24.
Porteus, M. (2016). Genome editing: a new approach to human therapeutics. Annual review of pharmacology and toxicology, 56(1), 163-190.
Zhang, Y. (2019). Ethical issues in genome editing
using CRISPR/Cas9 system. Journal of Clinical Research & Bioethics, 10(1),
1000344
